271* Achieving sustained compliance with nebulised therapies in a paediatric CF population

Achieving Compliance in a Virtualized Environment

Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection

RATIONALE Arikace is a liposomal amikacin preparation for aerosol delivery with potent Pseudomonas aeruginosa killing and prolonged lung deposition. OBJECTIVES To examine the safety and efficacy of 28 days of once-daily Arikace in cystic fibrosis (CF) patients chronically infected with P aeruginosa. METHODS 105 subjects were evaluated in double-blind, placebo-controlled studies. Subjects we...

Persistance and Compliance with Osteroporosis Therapies Among Women in a Commercially Insured Population in the United States.

BACKGROUND Prior research has shown that rates of persistence and compliance with osteoporosis therapies are associated with significantly fewer vertebral, nonvertebral, and hip fractures. A number of studies have examined medication-taking behavior with oral bisphosphonates and teriparatide, and these 1-year persistence rates have ranged from 39.9% to 56.7%. Limited real-world data are availab...

Two-year persistence and compliance with osteoporosis therapies among postmenopausal women in a commercially insured population in the United States

This retrospective, observational study assessed 2-year persistence and compliance by treatment, route of administration, and dosing frequency in postmenopausal women initiating a new osteoporosis therapy. Two-year persistence and compliance rates were higher in women receiving injectables compared with oral agents. PURPOSE This study extends previous studies limited to 1-year follow-up by ex...

The eRapid Nebulizer for the Delivery of Inhaled Therapies for CF Information for CF Centers

Orally inhaled therapies are a cornerstone of lung health maintenance in CF. Topical application of drugs in the airways increases the efficacy and reduces the systemic exposure and toxicity of these agents. Most CF patients are treated with aerosolized therapies, and many take multiple inhaled drugs on a daily basis. Treatments for bronchodilation, inflammation, airway clearance and early or c...